I have been dealing with this issue for quite some time now. I'm running the newest version of Rider currently available (2022.2.3).
I'm not able to debug anything. When I try to debug (Projects, Tests, etc...) I get the following pop-up message:
I have reinstalled Rider multiple times without any luck. The issue started with version 2022.2.2, and after I updated to 2022.2.3 I assumed the problems would go away, but nothing has changed.